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KMID : 0357919850190010131
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Korean Journal of Pathology
1985 Volume.19 No. 1 p.131 ~ p.135
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Multiple Chorioangiomas of Placenta -A case report associated with repeated abortions and intrauterine fetal death-
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Abstract
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Chorioangioma is the most common primary tumor of the placenta. It is widely
accepted to be formed from hamartomatous proliferation of angioblastic cells in early
placenta. According to groups who systematically examined the placentas with the
greatest scrutiny, the incidence of chorioangioma is 1∼1.2% of all placentas examined.
The clinical implication of chorioangioina has been emphasized due to its high
association with hydramnios, antepartum and postpartum hemorrhage, premature onset of
labor, or intrauterine fetal distress or death.
The authors experienced a case of a 38-year old multigravida who had undergone 4
consecutive spontaneous abortions. The fifth pregnancy was carried to 35 weeks
whereupon a dead fetus was delivered. The Placenta was enlarged(950gm) with multiple
protruding nodules into the fetal surface. Microscopically the nodule was composed of
many villous structures lined by chorionic epithelium.
Within these structures was proliferation of endothelial lined capillaries some of which
demonstrated ectatic change.
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